I have been using Xamarin for a while and consistently I have come to realise a bug which causes Visual Studio to freeze. This happens when you’re loading a solution. In my case, if I make some changes to the properties window of anything which uses Android SDK save, close the solution without closing the properties page the next time I open that solution VS will fail to load it. I have to kill the VS process from the task manager. No matter what how many times I restart VS, the solution will never load.

I’m using VS2015. You need to close VS and then delete the .suo file from

.vs\<ProjectName>\v14\ 

folder

It is a hidden file so you need to show the file first using the following method http://www.isunshare.com/windows-10/show-hidden-files-and-folders-in-windows-10.html